NeuroMorpho.Org

Overview

NeuroMorpho.Org is a centrally curated repository of digitally reconstructed neuron and glia morphologies, hosted at George Mason University and funded by the NIH. Launched in 2006, it is the primary open archive for neuronal morphology data, covering reconstructions from all animal species and brain regions. Submissions are moderated manually: curators verify the data, complete annotations, and index each reconstruction before publication. All morphologies are standardised in SWC format, enabling cross-study comparison and computational modelling. The repository surpassed 100,000 reconstructions in 2018 and held over 260,000 three-dimensional neural tracings from more than 1,000 contributing laboratories as of 2024. An agile release model introduced since 2020 reduced average time from data identification to public release from several months to under 40 days. The repository is not recommended for identifiable human data.

Connections

• implements: SWC
• isPartOf: NIF

Resources

• https://neuromorpho.org
• https://neuromorpho.org/myfaq.jsp (submission and FAQ)
• https://doi.org/10.1038/sdata20186 (Akram et al. 2018, Scientific Data, repository overview)
• https://pmc.ncbi.nlm.nih.gov/articles/PMC11226999/ (Ascoli et al. 2024, agile release model)
• https://incf.org/new-version-neuromorpho-released-100k-digital-reconstructions-available (100k milestone announcement, 2018)