Wellcome Sanger Institute
Overview
The Wellcome Sanger Institute is a genomics research institute at the Wellcome Genome Campus in Hinxton, Cambridgeshire, that has operated a formal rapid-release open data sharing policy since its founding in 1992 and is a major source of openly available neurological disease genetics and brain transcriptomics data. It is a founding co-leader of the Human Cell Atlas and deposits large-scale open datasets spanning brain single-cell transcriptomics, neurological disorder GWAS summary statistics, and population genomics to EGA, ENA, EVA, and CELLxGENE. It is co-located with EMBL-EBI and made the largest single institutional contribution to the Human Genome Project.
Notable datasets
Open-access brain single-cell transcriptomics datasets from the Sanger Institute’s cellular genetics programme are deposited to CELLxGENE and include large-scale atlas datasets covering multiple brain regions, cell types, and developmental stages. GWAS summary statistics for neurological and psychiatric disorders produced by the Sanger Institute are deposited to NHGRI-EBI GWAS Catalogue. Individual-level genomic and phenotypic data are deposited to EGA under managed access.
Connections
- registeredIn: EGA (controlled-access genomic and phenotypic data)
- registeredIn: ENA (open-access sequence data)
- registeredIn: EVA (open-access variant data)
- registeredIn: CELLxGENE (brain single-cell transcriptomics datasets)
- relatedTo: EMBL (co-located at Wellcome Genome Campus; EMBL-EBI operates shared infrastructure)