Brain/MINDS
Overview
Brain/MINDS (Brain Mapping by Integrated Neurotechnologies for Disease Studies) is a national brain mapping programme funded by AMED and launched in 2014. Its primary goal is to produce a comprehensive multi-resolution atlas of the common marmoset brain, a non-human primate model chosen for its genetic tractability and relevance to human neurological and psychiatric disease. Brain/MINDS generates open multi-modal datasets including MRI, diffusion tractography, two-photon calcium imaging, viral tracing, and transcriptomics, deposited in a dedicated open-access data portal.
Scope and Datasets
Brain/MINDS Phase 1 (2014–2023)
Phase 1 focused on the marmoset brain atlas at molecular, cellular, circuit, and whole-brain levels. Data types include structural and diffusion MRI, two-photon microscopy, viral vector tracing, single-cell transcriptomics, and behavioural data. The Brain/MINDS data portal provides open access without registration, with lead institution RIKEN CBS.
Brain/MINDS Beyond (Phase 2, 2018–ongoing)
Phase 2 extends toward human brain imaging at population scale, with multi-site neuroimaging studies across Japanese research institutes. It includes psychiatric disorder datasets covering schizophrenia, depression, ASD, and OCD as part of the SRPBS Multi-Disorder Neuroimaging Dataset, deposited on OpenNeuro.
Connections
- Deposits in: OpenNeuro (SRPBS dataset)
Resources
- https://brainminds.jp/en/ (programme overview)
- https://dataportal.brainminds.jp (Brain/MINDS data portal)
- https://openneuro.org/datasets/ds002311 (SRPBS Multi-Disorder dataset on OpenNeuro)
- https://www.amed.go.jp/en/program/list/11/01/001.html (AMED programme page)