iGENSEQ — Genomics and Sequencing Platform
Overview
iGENSEQ is Paris Brain Institute’s next-generation sequencing (NGS) platform, one of ICM’s 10 core technological platforms. It provides a full suite of genomic sequencing services to ICM research teams and external academic and industrial collaborators, covering bulk transcriptomics, single-cell genomics, whole-genome and whole-exome sequencing, and targeted panels.
Services
- RNA-seq covers bulk, stranded, total, or polyA-selected transcriptomics.
- Single-cell RNA-seq (scRNA-seq) uses droplet-based 10x Genomics technology.
- Whole-genome sequencing (WGS) covers both germline and somatic applications.
- Whole-exome sequencing (WES) uses targeted coding variant capture.
- Targeted panels include custom and commercial gene panels.
- ChIP-seq and ATAC-seq cover chromatin and epigenomics.
- Long-read sequencing using Oxford Nanopore is available for selected applications.
Open Science Connections
- Sequencing data from publications is deposited in NCBI GEO (open access).
- Variant calls are produced in VCF format.
- iGENSEQ is the primary downstream user of Banque ADN et Cellules DNA and RNA stocks.
- Analysis pipelines run in collaboration with DAC.
Connections
- Hosted at: Paris Brain Institute
- Labelled by: IBiSA
- Member of: France Génomique
- Upstream biobank: Banque ADN et Cellules
- Data deposit: NCBI GEO