ADNI — Alzheimer’s Disease Neuroimaging Initiative

Overview

ADNI is a longitudinal multicenter study tracking MRI, PET, biomarkers, clinical, and genetic data across the Alzheimer’s disease spectrum. It is one of the most widely used open clinical neuroimaging datasets, accessible via the LONI Image and Data Archive.

Key Outputs

• ADNI has enrolled 2,000+ participants across phases ADNI1, GO, 2, 3, and 4.
• Data types include MRI, amyloid, tau, and FDG PET, CSF, genetics, and cognitive data.
• Imaging protocols are harmonised across North America.

Connections

• Primary data archive: LONI IDA

Resources

• https://adni.loni.usc.edu
• https://adni.loni.usc.edu/data-samples/access-data/ (data access portal)
• https://adni.loni.usc.edu/study-design/ (study design overview)
• https://doi.org/10.1016/j.jalz.2010.03.004 (Jack et al. 2010 — ADNI design paper)